Human Platelet Lysate versus Fetal Calf Serum: These Supplements Do Not Select for Different Mesenchymal Stromal Cells
نویسندگان
چکیده
منابع مشابه
MESENCHYMAL STROMAL CELLS IMPLANTATION IN COMBINATION WITH PLATELET LYSATE PRODUCT IS SAFE FOR RECONSTRUCTION OF HUMAN LONG BONE NONUNION
This was Presented in 5th International Congress of Iranian Iranian Society of Knee Surgery, Arthroscopy, and Sports Traumatology (ISKAST), 14-17 Feb 2018- Kish, Iran
متن کاملhuman platelet lysate as a xeno free alternative of fetal bovine serum for the in vitro expansion of human mesenchymal stromal cells
background: mesenchymal stromal cells (mscs) are employed in various different clinical settings in order to modulate immune response. human autologous and allogeneic supplements including platelet derivatives such as platelet lysate (pl), platelet-released factors (prf) and serum are assessed in clinical studies to replace fetal bovine serum (fbs). the immunosuppressive activity and multi-pote...
متن کاملHuman Platelet Lysate as a Xeno Free Alternative of Fetal Bovine Serum for the In Vitro Expansion of Human Mesenchymal Stromal Cells
BACKGROUND Mesenchymal stromal cells (MSCs) are employed in various different clinical settings in order to modulate immune response. Human autologous and allogeneic supplements including platelet derivatives such as platelet lysate (PL), platelet-released factors (PRF) and serum are assessed in clinical studies to replace fetal bovine serum (FBS). The immunosuppressive activity and multi-poten...
متن کاملmesenchymal stromal cells implantation in combination with platelet lysate product is safe for reconstruction of human long bone non:union:
objective: non:union: is defined as a minimum of 9 months since injury without any visible progressive signs of healing for 3 months. recent literature has shown that the application of mesenchymal stromal cells is safe, in vitro and in vivo, for treating long bone non:union:. the present study was performed to investigate the safety of mesenchymal stromal cell (msc) implantation in combination...
متن کاملUmbilical Cord Blood Platelet Lysate as Serum Substitute in Expansion of Human Mesenchymal Stem Cells
OBJECTIVES The diverse clinical applications for human mesenchymal stem cells (hMSCs) in cellular therapy and regenerative medicine warrant increased focus on developing adequate culture supplements devoid of animal-derived products. In the present study, we have investigated the feasibility of umbilical cord blood-platelet lysate (UCB-PL) as a standard substitute for fetal bovine serum (FBS) a...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2017
ISSN: 2045-2322
DOI: 10.1038/s41598-017-05207-1